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Applications

Cell Biology

Like all electron microscopes, the LVEM can aid life science researchers by imaging tissue and cellular structure from the micron range to the nanoscale. Furthermore the LVEM can do so from within your lab group location, operated by your lab group members and provide results in both transmission (ultrastructure) and scanning (surface detail) modes.

Most advantageous is the fact that no staining is required to achieve highly contrasted results.

Whether you are studying proteins, cellular structures or using labels, the LVEM will be a powerful tool in your research.

TEM image of muscular synapse. scalebar = 600 nm
TEM image of muscular synapse.
Scalebar = 600 nm

Click to enlarge
TEM image of Muscle. Scalebar = 1.5 µm
TEM image of Muscle.
Scalebar = 1.5 µm

Click to enlarge
TEM image of Heart. Scalebar = 2 µm
TEM image of Heart.
Scalebar = 2 µm

Click to enlarge
TEM image of Grasshopper muscle. Scalebar = 1.5 µm
TEM image of Grasshopper muscle.
Scalebar = 1.5 µm

Click to enlarge


Education

Research equipment generally plays a major role in education as would-be scientists are exposed to the tools that are used to produce experimental results.

When that tool can provide a breadth of results and allows for hands-on use by the students then the investment is maximized.

The LVEM as a research tool is valuable in providing images at the micron and nano scale in both transmission (TEM) and scanning (SEM & STEM) modes. Furthermore, with some basic training, the system can be operated by students who gain a high level of experience and comfort with the a common tool of scientists – the electron microscope.

The ability to install the system in practically any location allows a set up that optimizes the learning experience with a minimal investment. In fact, the LVEM5 was selected for installation in a mobile van – The Nanoexpress at Howard University – due to the combination of its small size, easy installation and relevance to nanotechnology research.



Material Science

The LVEM is an imaging tool that is optimal for research across a broad range of materials science applications.

Based on its versatility (TEM, SEM and STEM imaging together with electron diffraction pattern generation) as well as its ability to produce highly contrasted results of light element samples – and of highly contrasted nanoparticles in profile- the LVEM excels as a research tool for the material scientist.

The LVEM has been used extensively in polymer research, as well as in imaging biomaterials, nanoparticles, nanotubes and difficult to observe materials including silk fibers. The LVEM can also be used to image all matters of samples in SEM mode regardless the elemental atomic (Z) number or weight.

The LVEM is easy to install practically anywhere, including in clean rooms and individual research group facilities.

SEM image of MgO crystals SEM image of MgO crystals
Click to enlarge
TEM image of Multi Walled Nanotubes. Scalebar = 750 nm TEM image of Multi Walled Nanotubes.
Scalebar = 750 nm

Click to enlarge
SEM Image of Nanotubes in Polymer Foam. Scalebar = 200 nm SEM image of Nanotubes in Polymer
Foam. Scalebar = 200 nm

Click to enlarge
SEM image of Polystyrene beads SEM image of Polystyrene beads
Scalebar = 20 µm

Click to enlarge


Pathology

The LVEM can play an important role in Pathology – at both the research and diagnostic levels.

The high contrast of LVEM results, matched with its quick time-to-image converts to better images with a smaller turnaround time. Several efforts have focused on the LVEM as a rapid diagnostic tool to identify infectious agents and the system is as easily comfortable in its role as a tool to capture nanoscale details in pathology research.



Drug Discovery

The LVEM can play a critical role in drug discovery efforts focused on materials characterization and morphology.

In addition to the high contrast of most drug discovery related samples, the LVEM is a quick load electron microscope with a rapid time-to-vacuum-ready (2-5 minutes). When the ability to install the LVEM where the research is undertaken is added to this equation, the result is a significant reduction in time to results.

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